This document outlines the Joint United Nations Programme on HIV/AIDS (UNAIDS) 2016-2021 strategy to end the AIDS epidemic as a public health threat by 2030. The strategy maps out the UNAIDS Fast-Track approach to accelerating the AIDS response over the next five years with the aim of reaching the following goals or milestones by 2020: fewer than 500,000 people newly infected with HIV, fewer than 500,000 people dying from AIDS-related causes, and elimination of HIV-related discrimination. By reaching these targets, the strategy hopes to be on track towards ending the epidemic by 2030, when the target is Zero new HIV infections, Zero discimination, and Zero AIDS-related deaths.